This piece will identify some of my favorite NFL DFS stacks of the weekend. Be sure to use our Stacking tool within our Player Models to find the highest projected stacks, the stacks that figure to be chalky, and more. Our Correlation Dashboard is also an excellent resource for finding hidden edges in stacking positions and games.
You can also plug these stacks into our Lineup Builder to hand-build the rest of it, or you can optimize it with our projections. And if you like to create multiple lineups, our Lineup Optimizer allows you to effortlessly create up to 300 lineups.
The Lineup Optimizer has endless customization opportunities.
Oh yeah! And our SimLabs Lineup Generator gives you the ability to create advanced DFS lineups using the power of simulation.
You can check out our in-depth SimLabs guide here.
Week 10 NFL DFS Stacks and Picks
Brock Purdy + Deebo Samuel + George Kittle + Cade Otton
- Brock Purdy ($6,500 DraftKings, $8,100 FanDuel)
- Deebo Samuel ($6,900 DraftKings, $8,300 FanDuel)
- George Kittle ($5,800 DraftKings, $8,000 FanDuel)
- Cade Otton ($5,500 DraftKings, $6,400 FanDuel)
Sitting with a 4-4 record and coming off their bye week, the San Francisco 49ers still have all of their main goals well within reach. They are only a 0.5 game back of first place in the NFC West and are the only team in the division with a positive point differential.
Another huge advantage for the 49ers is finally getting back star running back Christian McCaffrey. He has yet to play a game this season due to injury after being the rushing leader by nearly 400 yards last season. Getting McCaffrey back is huge, but his price tag makes him difficult to prioritize in his first game back. Instead we will attack the 49ers passing attack that has shown upside recently.
Brock Purdy has not had the easiest path to success this season with all of the injuries to the 49ers skill position players, but he has still flashed a ceiling in a few games. Even though his completion percentage and quarterback rating are at a career-low, Purdy has done damage with his legs.
In each of his last two games, Purdy has had eight rushing attempts and scored three touchdowns on the ground. Since Week 3, Purdy has at least four rushing attempts in every single game, proving he is a dual-threat quarterback. However, this matchup against the Buccaneers sets up well for Purdy to air it out. They are allowing the most fantasy points to opposing quarterbacks this season at 23.1 points per game.
Losing Brandon Aiyuk to a season-ending injury was costly to the 49ers offense, but it also consolidated the receiving targets. In Week 8, when both Aiyuk and Jauan Jennings were out, Deebo Samuel and George Kittle each had a 29% target share. These are the top two targets for this 49ers team stack.
Samuel is currently projected to be the highest-owned wide receiver on this 10-game slate. In his last two games played, Samuel has 173 total receiving yards and 30 rushing yards. The Buccaneers are allowing 20.3 targets per game to wide receivers this season, which is the fourth-highest total in the league. With limited receiver options, that bodes well for a ceiling game from Samuel this week.
No tight end has been better this season than George Kittle. The eight-year stud is leading the 49ers in receiving yards, receptions, targets, and touchdowns. He is also leading the entire tight end position with 18.5 DraftKings points per game. The position is loaded again this week, but Kittle has the second-highest projected ceiling to Travis Kelce. The Buccaneers are second only to the Panthers in most fantasy points allowed to the tight end position. Everything is aligning for another Kittle ceiling performance.
In general, the 49ers offense sets up amazing despite this looking like a difficult matchup on the road against the Buccaneers. They are implied for a slate-high 28.5 points and are nearly touchdown favorites. The Buccaneers are allowing 27 points per game, and 44.8% of opposing teams’ drives end up with a score, which is the sixth-highest in the league. Even with McCaffrey back, target the passing attack.
Playing a double tight end lineup used to be a “no-no”, but it has been profitable recently and that is the way we are going with this stack. With Chris Godwin and Mike Evans out, along with several other wide receivers still not practicing on Thursday, Cade Otton is in store for another monster game. In each of his last three games, Otton has eight or more receptions with double-digit targets. He is averaging 86 receiving yards and 23.9 DraftKings points per game, with three touchdowns and a 26% target share.
Good luck finding that type of production at the tight end position or for a wide receiving and running back around his price range. Double tight end will make this game stack unique with plenty of upside.
This 49ers and Buccaneers matchup is the only game on the slate with above a 50-point game total.
Don’t forget to check out our SimLabs Lineup Generator to create advanced DFS lineups using the power of simulation:
Sam Darnold + Aaron Jones + Justin Jefferson
- Sam Darnold ($6,200 DraftKings, $7,800 FanDuel)
- Aaron Jones ($6,700 DraftKings, $7,900 FanDuel)
- Justin Jefferson ($8,800 DraftKings, $9,500 FanDuel)
The Minnesota Vikings offense did not look great for most of last week’s game against the Indianapolis Colts, but they managed to score when it mattered most to get their first win after back-to-back losses.
Week 10 will offer a cupcake matchup for the Vikings going on the road against the Jaguars. They are seven-point road favorites, implied for 25.5 points. With Jaguars quarterback Trevor Lawrence’s status in doubt for Sunday, we will not force a bring-back in this stack and onslaught the Minnesota Vikings.
The Jaguars defense has been one of the best to attack this season. They come into Week 10 ranking 31st in defensive DVOA while allowing 28 points and 389.3 yards per game, both of which rank in the bottom three of the league. This is a great spot for the Vikings to flex their talent against a pitiful Jaguars defense.
Sam Darnold is having the best year of his career being the quarterback of the Vikings. He has set career-highs in completion percentage and yards per attempt while throwing 17 touchdowns. His interceptions have spiked recently, but the Jaguars defense only has two interceptions all season.
The Vikings have done a great job with limiting Darnold’s drop backs to keep his efficiency at an all-time high. His 32.63 dropbacks per game rank 22nd among quarterbacks this season, and his completion percentage has blossomed to 69.5%, which is among the league’s best. Of course, it helps playing alongside one of the best wide receivers in the game, Justin Jefferson.
Leading the Vikings in every receiving statistic, Jefferson is coming off his best game of the season against the Colts. He caught seven receptions for a season-high 137 yards. However, it was just the third game all season where Jefferson failed to get into the end zone. His odds to hit paydirt this week on the DraftKings sportsbook is -105, which is very enticing in the betting markets.
Jefferson has the highest projected ceiling at the wide receiver position by over five DraftKings points in our model. He is the highest-priced skill position player, but this spot for a ceiling performance is fantastic. The best part is that Jefferson is only drawing 10% projected ownership, making him a smash play.
Aaron Jones has been an incredible addition to the Vikings offense. Despite rushing for a career-low 4.5 yards per carry, Jones has an elite role in this high-powered offense. No other running back on the Vikings has had an attempt inside the 5-yard line and Jones has also locked up 100% of the two-minute drill snaps in each of the past three games.
Where Jones makes his money is in the passing game. He is averaging a career-high 9.7 yards per catch and has caught 26 of his 29 targets for 245 yards. Jones will be one of the highest-owned running backs on the slate, but he is deserving in this matchup. He has a great opportunity for 100+ all-purpose yards for the fifth time this season. He fits in perfectly with a Darnold passing stack.
The Jaguars defense has also been susceptible to tight ends, which makes TJ Hockenson appealing, but similar to Christian McCaffrey I am taking a wait and see approach. Hockenson returned last week but only had four targets. With such a loaded tight end slate, it feels too risky to take add Hockenson to this stack in Week 10. No Jaguars are necessary for a bring-back. Load up on the most important Vikings pieces are watch them slice and dice the Jaguars’ awful defense this Sunday.
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