There are an abundance of tools at FantasyLabs to use for your NFL DFS lineups each week. Our most popular tools are our NFL Player Models, which house our NFL DFS projections from Sean Koerner.
You can use these projections in our models with our Lineup Builder to hand-build your lineups or use our Lineup Optimizer to effortlessly create up to 150 lineups for your NFL DFS tournaments.
In this article, we will go position by position, highlighting my favorite plays for both cash games and single-entry/three-max GPP contests. These plays are also viable in large field tournaments but do not focus on ownership percentages.
NFL DFS Cash Game + Single-Entry GPP Locks
NFL DFS Quarterback Picks
Jared Goff ($5,600 DraftKings, $7,400 FanDuel) Detroit Lions vs. Chicago Bears
Goff has been playing some great football of late, having thrown for 330 yards or more and at least two touchdowns in three of his past four games. Last week he torched the Panthers for 355 and three, despite being on the road. More on that in a moment.
Bears-Lions currently boasts the highest total on the Week 17 main slate at 52 points, while the Lions have the highest implied team total on the slate at a whopping 29 points. Thankfully for Goff and DFS players, the Lions are back home in the friendly confines of the Ford Field dome.
Goff holds arguably the biggest home/road splits among any quarterback in the NFL. He’s averaging 277 yards and has thrown 20 touchdowns compared to just three interceptions, good for 23.1 DraftKings points. On the road, he’s averaging just 248 yards passing, has thrown just six touchdowns compared to five picks and is averaging just 13.3 DraftKings points.
Despite that, and the fact that the Lions are fully healthy on offense right now, DraftKings inexplicably left Goff at just $5,600 this week. He will surely be popular, but it’s hard to envision him failing at this salary against a Bears team allowing the eight most DraftKings points to opposing quarterbacks.
Justin Fields ($7,900 DraftKings, $8,400 FanDuel) Chicago Bears @ Detroit Lions
On the other side of this game is Justin Fields, who could potentially go overlooked after last week’s 9.9 DraftKings-point performance against the Bills. Despite dealing with shoulder and foot issues, the Bears are, for some reason, fully intent on playing their franchise quarterback in these two final (meaningless) games.
Being that as it may, Fields is one of the best overall quarterback plays on the slate. There is really not a whole lot to like at the top of the board despite this being a 13-game slate. We have no Josh Allen, Joe Burrow, Jalen Hurts, Lamar Jackson or Dak Prescott, while Patrick Mahomes is extremely pricy for his matchup, and Justin Herbert has questions surrounding his playing time.
This leaves Fields, who has a pristine matchup against a Lions defense allowing the most DraftKings points to opposing quarterbacks on the year. He should run a bit more than he did last week against a really tough Bills defense (nine attempts), keeping both his floor and ceiling extremely high in this likely shootout.
NFL DFS Running Back Picks
Travis Etienne Jr. ($6,400 DraftKings, $7,700 FanDuel) Jacksonville Jaguars @ Houston Texans
Doug Pederson has already come out and said the Jaguars will play all their starters this week, yet for some reason, Etienne seems to be going overlooked. He’s playing the Texans, a team that’s allowed the most rushing attempts, rushing yards, and rushing touchdowns in the NFL this season, and costs only $6,400 on DraftKings. What am I missing here?
He saw 22 carries against the Jets and got vultured at the goal line by his quarterback. Otherwise, his DraftKings score would have looked flashier. In addition, he’s been seeing some work in the passing game of late, catching five of six targets for a combined 63 yards over his past two games.
If Doug Pederson is telling the truth and the Jags play this game straight up, there’s zero reason to think Etienne will not smash this Texans team.
Brian Robinson Jr ($5,200 DraftKings, $6,900 FanDuel) Washington Commanders vs. Cleveland Browns
I usually don’t advocate playing a yardage and touchdown back on a bad offense that’s also in a timeshare. However, Antonio Gibson will be out this week, which is not reflected in Robinson’s price on DraftKings. His only competition for touches will be Jonathan Williams, who has 13 carries on the season. The Browns have been an abject disaster since Deshaun Watson took back the starting quarterback job, so there is a good chance Robinson will find himself in a positive game script.
Cleveland has also been gutted by opposing running backs this year, having allowed the third most rushing touchdowns and DraftKings points to the position. At just $5,200, Robinson is just too cheap for his projected role.
NFL DFS Wide Receiver Picks
Amon-Ra St. Brown ($7,800 DraftKings, $8,200 FanDuel) Detroit Lions vs. Chicago Bears
St. Brown is in the best spot of any wide receiver on the slate this week, especially among the higher end of the salary range. Much like his quarterback, ARSB has done his best work at home this season, averaging 24 DraftKings points compared to just 12.9 on the road.
He’s seen 10 or more targets in four of his past five games and should easily challenge double digits again this week. The Bears have also allowed the second-highest yards per reception to opposing wideouts on the season, so there’s some serious splash play potential here.
When you factor in matchup, salary, and opportunity cost at the position this week, St. Brown stands out like a sore thumb. Once again, the Lions boast a 29-point implied team total.
Garrett Wilson ($5,500 DraftKings, $7,300 FanDuel) New York Jets @ Seattle Seahawks
Mike White is back under center for the Jets this week, which means we must put Garrett Wilson back in our lineups. DraftKings did us a favor by pricing him as if Zach Wilson was still starting, leaving him simply too cheap at just $5,500. In three games that White has started this year, Wilson’s stat lines read: 5/95/2, 8/162/0 (15 targets) and 6/78/0 (Buffalo). White only has eyes for the Ohio State product, it appears.
Seattle has done a good job of limiting perimeter receivers this season, but volume usually trumps efficiency in fantasy football, and Wilson is projected for quite a bit of volume for just $5,500.
NFL DFS Tight End Picks
George Kittle ($5,900 DraftKings, $7,400 FanDuel) San Francisco 49ers @ Las Vegas Raiders
Deebo Samuel has missed each of the past two games with his ankle injury, and in those two games, Kittle has gone 4/93/2 and 6/120/2. Yeah, that’ll work. The train should keep rolling, as Deebo has been ruled out again this week against the Raiders. It really does not seem to matter who’s at quarterback for the 49ers, as Brock Purdy has stepped right in and run the Shanahan scheme to perfection.
Paying up for non-Travis Kelce tight ends is usually a big no-no. However, there’s no way someone could argue Kittle is not too cheap at just $5,900 against a Raiders team that’s all but packed it in for the season. It’s not unreasonable to think Kittle could outscore Kelce this week, and he’s $2,200 cheaper than him on DraftKings. This is more of a tournament play, but if someone showed up with Kittle in a cash game against me, I certainly would not call them a fish.
Jelani Woods (2,800 DraftKings, $4,700 FanDuel) Indianapolis Colts @ New York Giants
If you prefer to punt the tight end position, Woods stands out as a pretty strong option this week. He looked like he was gonna go nuclear against the Chargers last week after posting 32 yards in the first quarter, but Nick Foles turned into a pumpkin and completely derailed the Colts offense. The good news is that fellow tight end Kylen Granson is out again this week, which should give Woods ample playing time in this spot.
The Giants rank 27th in the NFL in DK points allowed to opposing tight ends and are allowing the third-highest catch rate to the position.
At $2,800, you can certainly do far worse.
YOU MAY ALSO LIKE
Understanding Ceiling Projections for NFL DFS Tournaments
NFL DFS Showdown: Lineup Optimizer Rules and My Favorite Angle in Chargers vs. Chiefs
Steelers-Browns Same Game Parlay: NFL Player Prop Picks, Over/Under, More, Using Parlay IQ for Thursday Night Football
Week 4 NFL DFS Top Model Picks and Value Plays on DraftKings and FanDuel
